HORDB

ID: hor003376
Uniprot ID: A0A158TFP8
Protein name: Orcokinin
Gene name: ORCK
Organism: Cancer borealis (Jonah crab)
Family: Orcokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Cancer (genus), Cancridae (family), Cancroidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: NFDEIDRSGFG
Length: 11
Propeptide: MTRDVICTALLLALCVMASEGAIKDTPTHPANQPDAGYPADGSAAKRFDAFTTGFGHSKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSGFGFAKRNFDEIDRSSFGFNKRNFDEIDRSSFGFVKRMLTPRDLANLYKRNFDEIDRSGFGFVRRNAE
Signal peptide: MTRDVICTALLLALCVMASEG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003376_AF2.pdb

hor003376_ESM.pdb

Mass:	143484	Formula:	C54H77N15O20
Absent amino acids:	ACHKLMPQTVWY	Common amino acids:	DFG
pI:	3.88	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	3
Hydrophobicity:	-90.91	Boman Index:	-3645
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	35.45
Instability Index:	5724.55	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 19185513
Title: Measurement of Neuropeptides in Crustacean Hemolymph via MALDI Mass Spectrometry